Science-backed insights on regenerative medicine, longevity, and the therapies reshaping how we think about repair, recovery, and the biology of aging.
Browse articlesThere’s a lot of information out there about regenerative medicine. These articles explain the compounds and therapies people ask us about, what the research shows, and where there are still questions. You’ll find links to the studies if you’d like to look into them further.
Every reference is verified against its primary source before it is published. Citations link to PubMed, ClinicalTrials.gov and FDA labelling, so you can read the underlying study rather than take our summary on trust. The library grows as we work through the compounds used in our protocols.
The articles are educational. They are not medical advice, and the right therapy depends on your history and your goals, which is a conversation to have with a qualified clinician.
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What happened when senolytics were tested in people? The findings from bone, lung and Alzheimer's studies, including the results that did not show benefit.
Read Article LongevityWhat is behind a biological age result? How the clocks differ, what human trials have found, and the questions worth asking before paying for a test.
Read Article MetabolicThe GLP-1 behind Ozempic and Wegovy. It mimics a gut hormone to curb appetite and blood sugar, drove about 15% weight loss in the STEP 1 trial, and cut cardiovascular events by 20% in SELECT.
Read Article MetabolicA small-molecule NNMT inhibitor explored for fat loss and metabolic health, working upstream of NAD+ to shift fat cells toward burning more energy. Animal studies are encouraging, with human research as the next step.
Read Article MetabolicA synthetic piece of human growth hormone engineered to switch on fat burning, AOD9604 showed clear lipolytic activity in animal models and went on to a full human obesity-trial program with a strong safety record.
Read Article Chronic IllnessBicyclol is a liver-protective drug with a genuine human evidence base: randomized trials and a meta-analysis show it reliably lowers elevated liver enzymes in drug-induced liver injury and fatty liver disease.
Read Article Metabolic5-aminolevulinic acid is the body's own first step in making heme; paired with iron it supplies the building blocks for red blood cells and the mitochondrial enzymes that power cellular energy, with human trials in blood-sugar control and active mitochondrial-protection studies.
Read Article PeptidesA Khavinson short peptide (Ala-Asp-Glu-Leu) directed at the airway lining: early cell and animal research links it to bronchial epithelium repair and calmer airway inflammation.
Read Article MetabolicRetatrutide is a triple-hormone receptor agonist (GIP, GLP-1, and glucagon) studied for obesity, type 2 diabetes, and liver fat. Phase 2 trials showed about 24% average weight loss, and large phase 3 trials are now underway.
Read Article PeptidesPT-141 (bremelanotide) is a melanocortin agonist that works through the brain rather than blood flow. It is FDA-approved as Vyleesi for low sexual desire in premenopausal women and is now being studied for weight management.
Read Article PeptidesBPC-157 is a synthetic peptide derived from gastric juice, studied for tendon, ligament, and gut healing. Most of the evidence so far is from animal models, with the first human trials now beginning.
Read Article PeptidesTB-500 is a synthetic fragment of thymosin beta-4, a natural tissue-repair protein. Research points to roles in healing, recovery, and flexibility, so far mainly in preclinical models.
Read Article NeurologicalNVG-291 is a peptide designed to release a natural brake on nerve regrowth by targeting the PTP-sigma receptor. The early evidence is preclinical, with human trials now beginning.
Read Article PeptidesARA-290 (cibinetide) is an erythropoietin-derived peptide that activates the body's innate repair pathway without raising red blood cell counts. It has been tested in randomized human trials for small fiber neuropathy.
Read Article NeurologicalCerebrolysin is a neuropeptide preparation studied for stroke recovery, traumatic brain injury, and vascular dementia, with decades of clinical trials and meta-analyses behind it.
Read Article LongevitySS-31 (elamipretide) is a peptide that targets cardiolipin in the mitochondria to support cellular energy. It has been tested in human trials, including phase 3, for mitochondrial disease and heart failure.
Read Article PeptidesVIP (vasoactive intestinal peptide) is a peptide the body makes naturally, with broad anti-inflammatory and immune-modulating effects studied in conditions including lung disease.
Read Article PeptidesGHK-Cu is a naturally occurring copper peptide that declines with age, studied for skin regeneration, wound healing, and tissue repair.
Read Article PeptidesKPV is a small three-amino-acid fragment of alpha-MSH studied for its anti-inflammatory effects, especially in the gut. The mechanism is well described, with human data still early.
Read Article NeurologicalSemax is an ACTH-derived neuropeptide studied for stroke recovery and cognition, with much of its clinical research base in Russia.
Read Article PeptidesSelank is a tuftsin-derived peptide studied for anxiety, including trials comparing it head-to-head with benzodiazepines, much of the research from Russia.
Read Article PeptidesDSIP (delta sleep-inducing peptide) is a naturally occurring neuropeptide tied to deep sleep, studied in early controlled trials for insomnia.
Read Article PeptidesCJC-1295 is a long-acting GHRH analog studied for its ability to raise the body's own growth hormone and IGF-1 for days at a time.
Read Article PeptidesIpamorelin is a selective growth hormone secretagogue studied for prompting the body's own growth hormone, including research on gut recovery after surgery.
Read Article PeptidesTesamorelin is a GHRH analog FDA-approved for HIV-associated visceral fat, with randomized-trial evidence for reducing liver fat and emerging research in muscle and cognition.
Read Article LongevityHuman growth hormone is a tightly regulated prescription hormone. This article covers what the research supports, why diagnosis matters, and how it is used responsibly under physician care, not as an anti-aging shortcut.
Read Article LongevityNAD+ is a coenzyme central to cellular energy and repair that declines with age. We look at what human research shows on supporting metabolism and healthy aging.
Read Article Stem CellsMesenchymal stem cells (MSCs) work mainly as signaling and immune-modulating cells. They are among the most studied cells in regenerative medicine, with trials across osteoarthritis and immune disease.
Read Article Stem CellsUmbilical cord-derived MSCs are immune-modulating stem cells from donated cord tissue, studied across inflammatory and immune-driven conditions.
Read Article Stem CellsMUSE cells are a stress-tolerant subset of stem cells with natural repair and homing ability, studied for stroke and heart repair.
Read Article Stem CellsThree tissues supply nearly all stem cell therapy and they are not interchangeable. How the sources differ, and the preparation divide that matters more than any of them.
Read Article Stem CellsTwo vials with the same label can hold different medicines. Donation, expansion, passage number, potency testing, and the post-thaw viability numbers to ask for.
Read Article ReprogrammingAdult cells sent back to the beginning, able to become any tissue. Why nobody transplants them directly, and how far the human trials have actually come.
Read Article Stem CellsThey set the standard every other stem cell is measured against, then the field found a better route. What the trials showed, and why cord cells are not embryonic.
Read Article ReprogrammingFour genes can return an adult cell to a stem-cell state, resetting its age markers along with its identity. The Nobel-winning discovery behind modern cell reprogramming.
Read Article LongevityThe most heavily funded idea in longevity science: pulse the reprogramming factors briefly to reset a cell's age without erasing what it is. What the animal work shows.
Read Article Stem CellsExosomes carry the repair signals of stem cells without the cells themselves. What they are, where they come from, and why the source cell decides the cargo.
Read Article LongevityCord blood plasma and alpha-fetoprotein (AFP) sit at the intersection of young-blood biology and immune regulation, an early and actively studied area of regenerative research.
Read Article MetabolicLow-dose naltrexone (LDN) is an off-label use of an approved drug, studied for fibromyalgia and chronic pain through its effects on inflammation and pain signaling.
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