Insights

Science-backed insights on regenerative medicine, longevity, and the therapies reshaping how we think about repair, recovery, and the biology of aging.

Metabolic

Retatrutide: A Triple-Hormone Weight-Loss Agonist

Retatrutide is a triple-hormone receptor agonist (GIP, GLP-1, and glucagon) studied for obesity, type 2 diabetes, and liver fat. Phase 2 trials showed about 24% average weight loss, and large phase 3 trials are now underway.

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Peptides

PT-141 (Bremelanotide): FDA-Approved for Low Libido

PT-141 (bremelanotide) is a melanocortin agonist that works through the brain rather than blood flow. It is FDA-approved as Vyleesi for low sexual desire in premenopausal women and is now being studied for weight management.

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Peptides

BPC-157: A Tissue and Gut Repair Peptide

BPC-157 is a synthetic peptide derived from gastric juice, studied for tendon, ligament, and gut healing. Most of the evidence so far is from animal models, with the first human trials now beginning.

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Peptides

TB-500: A Tissue-Repair Peptide

TB-500 is a synthetic fragment of thymosin beta-4, a natural tissue-repair protein. Research points to roles in healing, recovery, and flexibility, so far mainly in preclinical models.

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Neurological

NVG-291: A Peptide for Nerve Regrowth

NVG-291 is a peptide designed to release a natural brake on nerve regrowth by targeting the PTP-sigma receptor. The early evidence is preclinical, with human trials now beginning.

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Peptides

ARA-290 (Cibinetide): A Peptide for Nerve Repair

ARA-290 (cibinetide) is an erythropoietin-derived peptide that activates the body's innate repair pathway without raising red blood cell counts. It has been tested in randomized human trials for small fiber neuropathy.

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Neurological

Cerebrolysin: A Neuropeptide for Brain Recovery

Cerebrolysin is a neuropeptide preparation studied for stroke recovery, traumatic brain injury, and vascular dementia, with decades of clinical trials and meta-analyses behind it.

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Longevity

SS-31 (Elamipretide): A Mitochondria-Targeting Peptide

SS-31 (elamipretide) is a peptide that targets cardiolipin in the mitochondria to support cellular energy. It has been tested in human trials, including phase 3, for mitochondrial disease and heart failure.

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Peptides

VIP: The Body's Anti-Inflammatory Peptide

VIP (vasoactive intestinal peptide) is a peptide the body makes naturally, with broad anti-inflammatory and immune-modulating effects studied in conditions including lung disease.

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Peptides

GHK-Cu: The Copper Peptide for Skin Repair

GHK-Cu is a naturally occurring copper peptide that declines with age, studied for skin regeneration, wound healing, and tissue repair.

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Peptides

KPV: An Anti-Inflammatory Peptide

KPV is a small three-amino-acid fragment of alpha-MSH studied for its anti-inflammatory effects, especially in the gut. The mechanism is well described, with human data still early.

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Neurological

Semax: A Peptide for Brain Recovery

Semax is an ACTH-derived neuropeptide studied for stroke recovery and cognition, with much of its clinical research base in Russia.

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Peptides

Selank: An Anti-Anxiety Peptide

Selank is a tuftsin-derived peptide studied for anxiety, including trials comparing it head-to-head with benzodiazepines, much of the research from Russia.

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Peptides

DSIP: The Deep-Sleep Peptide

DSIP (delta sleep-inducing peptide) is a naturally occurring neuropeptide tied to deep sleep, studied in early controlled trials for insomnia.

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Peptides

CJC-1295: A Long-Acting GHRH Analog

CJC-1295 is a long-acting GHRH analog studied for its ability to raise the body's own growth hormone and IGF-1 for days at a time.

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Peptides

Ipamorelin: A Selective GH Secretagogue

Ipamorelin is a selective growth hormone secretagogue studied for prompting the body's own growth hormone, including research on gut recovery after surgery.

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Peptides

Tesamorelin: FDA-Approved for Visceral Fat

Tesamorelin is a GHRH analog FDA-approved for HIV-associated visceral fat, with randomized-trial evidence for reducing liver fat and emerging research in muscle and cognition.

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Longevity

Growth Hormone (HGH): Replacement, Not Anti-Aging

Human growth hormone is a tightly regulated prescription hormone. This article covers what the research supports, why diagnosis matters, and how it is used responsibly under physician care, not as an anti-aging shortcut.

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Longevity

NAD+: The Cellular Energy Coenzyme

NAD+ is a coenzyme central to cellular energy and repair that declines with age. We look at what human research shows on supporting metabolism and healthy aging.

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Stem Cells

MSC Therapy: The Body's Repair Signals

Mesenchymal stem cells (MSCs) work mainly as signaling and immune-modulating cells. They are among the most studied cells in regenerative medicine, with trials across osteoarthritis and immune disease.

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Stem Cells

Umbilical Cord MSCs: Immune-Modulating Stem Cells

Umbilical cord-derived MSCs are immune-modulating stem cells from donated cord tissue, studied across inflammatory and immune-driven conditions.

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Stem Cells

MUSE Cells: Stress-Tolerant Repair Cells

MUSE cells are a stress-tolerant subset of stem cells with natural repair and homing ability, studied for stroke and heart repair.

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Stem Cells

MUSE & MSC Exosomes: Repair Signals, No Cells

MUSE and MSC exosomes carry the repair signals of stem cells without the cells themselves, an emerging cell-free approach to regenerative therapy.

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Longevity

Cord Blood Plasma & AFP: The Young-Blood Research

Cord blood plasma and alpha-fetoprotein (AFP) sit at the intersection of young-blood biology and immune regulation, an early and actively studied area of regenerative research.

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Metabolic

Low-Dose Naltrexone (LDN): Studied for Chronic Pain

Low-dose naltrexone (LDN) is an off-label use of an approved drug, studied for fibromyalgia and chronic pain through its effects on inflammation and pain signaling.

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